Poxet 60 MgMg results showed that dapoxetine does not alter the pharmacokinetic of tadalafil or sildenafil. classified as an antidepressant, or to be more specific, an SSRI (selective serotonin reuptake inhibitor). However, medical researchers noted... morePoxet 60 MgMg results showed that dapoxetine does not alter the pharmacokinetic of tadalafil or sildenafil. classified as an antidepressant, or to be more specific, an SSRI (selective serotonin reuptake inhibitor). However, medical researchers noted that it acts much faster when compared to other antidepressants, and is also eliminated rapidly. This means that it is not effective enough to treat depression but it is ideal for PE, as its rapid action allows for patients to use it before intercourse.