As a Lyme disease therapy alternative, many health organizations are focusing on herbs and plant-based treatments. Trillium Health Solutions is a health company that sells a variety of Lyme disease supplements. Lyme disease is initially characterized by a rash, fever, headache, and lethargy. If you don't seek treatment right soon, the infection could spread to your joints, heart, and neurological system. Herbal remedies can effectively treat Lyme disease.